Valproxa ER-500 Tablets are an extended-release pharmaceutical formulation of divalproex sodium, designed for effective seizure control and mood stabilization. The long-acting, once-daily formulation provides stable plasma levels, helping suppress seizure activity, stabilize neuronal firing, and support mood regulation. It is indicated for epilepsy, bipolar disorder, and migraine prevention.
Valproxa ER-500 Tablets are an extended-release pharmaceutical formulation of divalproex sodium, designed for effective seizure control and mood stabilization. The long-acting, once-daily formulation provides stable plasma levels, helping suppress seizure activity, stabilize neuronal firing, and support mood regulation. It is indicated for epilepsy, bipolar disorder, and migraine prevention.
Epilepsy and seizure disorders Bipolar disorder (manic episodes) Migraine prophylaxis Mood stabilization
Dosage should be taken as prescribed by the physician.
Divalproex Sodium (Extended Release) – 500 mg
Divalproex Sodium ER (500 mg) works through multiple neurostabilizing mechanisms: Inhibits voltage-gated sodium channels → Reduces rapid neuronal firing and seizure propagation Modulates T-type calcium channels → Particularly effective in absence seizures Enhances GABAergic transmission → Increases GABA synthesis → Decreases GABA degradation Neuronal membrane stabilization → Suppresses abnormal electrical activity → Provides mood-stabilizing effects Overall Effect: These combined actions stabilize neuronal membranes, reduce seizure frequency, and support consistent mood control.
